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EnviarValium (diazepam):
| Humans: | ||
| Trade Name | Strength | Manufacturer |
| Valium | 2, 5, 10 mg tab | Roche Pharmaceuticals |
The drug Valium (diazepam) belongs to a class of drugs know as benzodiazepines, which as a group exhibit strong anticonvulsant, muscle relaxant, anti-anxiety and sedative properties. Valium is most commonly used as a general sedative, and for the treatment of acute anxiety disorders. This is because diazepam is shown to markedly relax the patient, and suppress feelings of panic and unrest (as with phobia cases). In some instances it is also used for the control of skeletal muscle spasms, and as an anti-seizure medication during alcohol withdrawal. This compound is manufactured as both an injection and tablet, the oral form of administration being the more widely prescribed. Here in the United States Valium is seen as a drug with a high potential for abuse. This has led it to be placed on the list of controlled substances, specifically a schedule IV item. Schedule four drugs by definition are likely to produce a notable psychological dependency when overused, with a lesser tendency to produce a physical addiction.
After oral administration, peak blood levels of this drug are reached within about 1 hour. Intravenous or intramuscular injections of course would provide a stronger and much faster effect. Diazepam is metabolized by the liver into various active metabolites, the primary structures being nordiazepam and oxazepam. These metabolites may therefore have an effect on the body for a noticeably long duration, with all active structures taking days (not hours) to be removed from the body. This has led many users to experience an unwelcome sluggish feeling, which sometimes is noticed for a day or two after the drug had been administered. It is additionally noted for giving the user a groggy feeling upon waking in the morning, the individual perhaps not feeling as fully rested or energetic as they would typically expect. Those who have a persistent complaint of this nature will generally switch to the agent Xanax, another benzodiazepine. This item has a much shorter half-life, and is eliminated by the body much more rapidly in comparison.
Bodybuilders (some anyway) are attracted to Valium for two specific reasons. Most use it as a basic sleep aid when strong stimulants like ephedrine, clenbuterol or thyroid hormones are being utilized. In many instances these drugs can give the user periodic bouts of insomnia, obviously an unwanted effect when he/she is scheduled for a morning workout. Along the same lines one may be welcoming the euphoric effect that is often reported with Valium use. This drug is clearly sought after as a recreational substance, and is commonly sold on the (non¬athletic) black market as "V's" or "Blues" (10mg Valium tablets are most often blue). This drug is also used for its ability to reduce the level of cortisol in the blood. This hormone, as you know, has a catabolic (muscle breakdown) effect. Since Valium (and benzodiazepines) can lower cortisol secretion, they may theoretically produce an anti¬catabolic effect, equating to new muscle growth/muscle retention as the action of cortisol is diminished. Many however, find the lethargy that Valium may produce is too much trouble for it to be taken regularly as a performance enhancer. Instead the user will make a trade-off, not taking the drug while training intensely, but taking Valium on a rest day when training is a little more relaxed (basically equating to recreational use).
The most common practice is to take 5-10mg at night if the athlete is simply using it as a sleep aid, or to increase the dose to 15-20mg when looking for a stronger euphoric effect. Using Valium as a recreational drug can bring fourth a number of health risks, the most prominent being the potential to abusively intake the substance. Since tolerance to this drug also occurs very quickly, the user can unfortunately begin a process of increasing the dosage in order to chase down an ever-diminishing effect. Withdrawal symptoms can also been seen with benzodiazepines, even when used at ordinary therapeutic doses for longer periods. For this reason the daily dosage should always be slowly reduced as long term therapy is halted.
The side effects most frequently encountered with Valium include drowsiness and over sedation. Less common are a depression of mood, disorientation, confusion, amnesia, lightheadedness, dizziness, lethargy, constipation, nausea, diarrhea and changes in libido. Most of these side effects seem to become persistent only as the dosage and duration of Valium therapy increases. Respiratory depression is also possible with very high doses of this drug, in rare instances leading to a cardiovascular collapse. A fatal overdose is in fact unlikely with Valium, unless a deliberately large quantity of tablets were to be consumed.
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