Lasilactone (spironolactone/furosemide) :
Manufactured extensively worldwide. trade names include:
|Duraspiron 50||50 mg / 20 mg tab||Durachemie G|
|Duraspiron 100||100 mg / 20 mg tab||Durachemie G|
|Furo-Aldopour||50 mg / 20 mg tab||Hormosan G|
|Furo-Aldopour forte||100 mg / 20 mg tab||Hormosan G|
|Lasilacton||100 mg / 20 mg tab||Hoechst A, CH|
|Lasilacton||50 mg / 20 mg tab||Hoechst A, CH|
|Lasilactone||50 mg / 20 mg tab||Hoechst GB|
|Osyrol 50||50 mg / 50 mg tab||Hoechst G|
|Osyrol 100||100 mg / 50 mg tab||Hoechst G|
|Spirolacton comp 50||50 mg / 20 mg tab||Heumann G|
|Spirolacton comp 100||100 mg / 20 mg tab||Heumann G|
Lasilactone is the Hoechst trade name for an oral, combination diuretic. Specifically, it contains a mixture of spironolactone (Aldactone®) and furosemide (Lasix). Aldactone® is a much milder, potassium sparing diuretic while Lasix is a notably potent compound from the family of loop agents. The combination of these two diuretics creates a drug with potency comparable to that seen with a much higher Lasix dosage (approximately double if used alone), but without the extreme level of calcium and potassium excretion. While a potassium supplement is often required with Lasix treatment, the balance of the two drugs in this compound will usually make this unnecessary. Medically, Lasilactone is used to treat cases of high blood pressure and edemas (swelling). When administered, diuresis (water excretion) becomes pronounced within an hour, and will remain notable for approximately four hours.
Like many patients, Athletes are attracted to diuretics because of their ability to remove stored water from the body. This effect is highly sought after by competitive bodybuilders, as a drop in subcutaneous water storage can increase the visibility of muscle features (increased definition). In sports where the competitor is restricted to a weight class (such as boxing and wrestling), diuretics are also extremely popular. They can be used to manipulate the bodyweight, in order for the athlete to make weight category adjustments. Since the "weigh-in" procedure is completed (generally) a day or days before the competition, the user has a clear window of opportunity to drop their bodyweight with a diuretic before hitting the scale. The long stretch of time after the weight in gives the user ample time to rehydrate, and as a result compete in a lower weight class than his/her bodyweight would dictate.
When administering this drug, the user will need to adjust the dosage in order to fit his or her individual needs. The most common practice is to administer a single 50mg/20mg tablet in the morning (with a meal), and to wait and judge the level of water loss. After a number of hours, this is repeated if a stronger diuretic effect is required. Usually no more than 2 or 3 tablets will be taken by the end of the day. This is perhaps repeated for a couple of more days, as the athlete looks to obtain the optimal result. So as to minimize any potential health risks, it is good advice to limit the use of such compounds to no more than a few days. It is also much more effective when the athlete is familiar with the whole process before using such drugs for a show/competition. Frantic, last minute diuretic use (due to poor planning) can easy lead to a troubling level of dehydration. The difference between a flat, deflated appearance and the all important defined (ripped) look is in many cases only a small dosage adjustment.
This diuretic (as all) can present a number of unwanted side effects to the user. This includes, but is not limited to, dehydration, cramping, diarrhea, dizziness, headache, anxiety, unrest, weakness, numbing of extremities and cardiac irregularities. One also risks severe dehydration, which has the potential to result in coma or death. Unfortunately athletes will too often take great risks, pushing their diuretic use to the limits of personal health. The line between a desired effect and serious complications is, in many instances, very fine. While serious side effects appear less frequently with compound diuretics as such, it should still remain a constant concern. Lasix in particular can be a very powerful compound and should be respected as such.